| Identification | Back Directory | [Name]
(S,R,S)-AHPC-amido-C5-acid | [CAS]
2162120-87-6 | [Synonyms]
(S,R,S)-AHPC-amido-C5-acid
7-(((S)-1-((2S,4R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-7-oxoheptanoic acid | [Molecular Formula]
C29H40N4O6S | [MDL Number]
MFCD32903593 | [MOL File]
2162120-87-6.mol | [Molecular Weight]
572.72 |
| Chemical Properties | Back Directory | [Boiling point ]
881.3±65.0 °C(Predicted) | [density ]
1.257±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C | [form ]
Solid | [pka]
4.75±0.10(Predicted) | [color ]
White to yellow |
| Hazard Information | Back Directory | [Biological Activity]
(S,R,S)-AHPC-amido-C5-acid incorporates a VHL ligand for the E3 ubiquitin ligase, and a PROTAC linker. (S,R,S)-AHPC-amido-C5-acid can be used to design XY028-133 [1]. | [storage]
Store at -20°C | [References]
[1]. Jian Jin, et al. Compositions and methods for treating cdk4/6-mediated cancer. WO2018106870A1. |
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