Identification | Back Directory | [Name]
NFκB Inhibitor | [CAS]
213546-53-3 | [Synonyms]
SN50 NFkB Inhibitor NF-KAPPA-B SN50 NF-κB Inhibitor, SN50 NF-KAPPAB INHIBITOR SN50 AAVALLPAVLLALLAPVQRKRQKLMP NF-κB Inhibitor, SN50, >=97% NUCLEAR FACTOR NF-B INHIBITOR SN50 NUCLEAR FACTOR NF-KAPPA-B INHIBITOR SN50 NF-KAPPA-B SN50, CELL-PERMEABLE INHIBITOR PEPTIDE NF-KAPPAB SN50, CELL-PERMEABLE INHIBITORY PEPTIDE FGF-4 PRECURSOR (7-22) (HUMAN)-EBP-1 (359-368) (HUMAN) HST-1 PRECURSOR (7-22) (HUMAN)-DNA-BINDING FACTOR KBF1 (359-368) (HUMAN) FIBROBLAST GROWTH FACTOR-4 PRECURSOR (7-22) (HUMAN)-NUCLEAR FACTOR NF-KAPPA-B P105 SUBUNIT (359-368) (HUMAN) H-ALA-ALA-VAL-ALA-LEU-LEU-PRO-ALA-VAL-LEU-LEU-ALA-LEU-LEU-ALA-PRO-VAL-GLN-ARG-LYS-ARG-GLN-LYS-LEU-MET-PRO-OH FGF-4 Precursor (7-22) (huMan)-EBP-1 (359-368) (huMan), HST-1 Precursor (7-22) (huMan)-DNA-Binding Factor KBF1 (359-368) (huMan), Fibroblast Growth Factor-4 Precursor (7-22) (huMan)-Nuclear Factor NF-ΚB p105 Subunit (359-368) (huMan) TFA L-Proline, L-alanyl-L-alanyl-L-valyl-L-alanyl-L-leucyl-L-leucyl-L-prolyl-L-alanyl-L-valyl-L-leucyl-L-leucyl-L-alanyl-L-leucyl-L-leucyl-L-alanyl-L-prolyl-L-valyl-L-glutaminyl-L-arginyl-L-lysyl-L-arginyl-L-glutaminyl-L-lysyl-L-leucyl-L-methionyl- | [Molecular Formula]
C129H230N36O29S | [MDL Number]
MFCD01076531 | [MOL File]
213546-53-3.mol | [Molecular Weight]
2781.5 |
Hazard Information | Back Directory | [Uses]
NFkappaB Inhibitor is inhibits translocation of the NFκB active complex into the nucleus. | [Biochem/physiol Actions]
SN50 is an NF-κB cell permeable inhibitory peptide. The SN50 sequence contains the nuclear localization sequence (NLS residues 360-369) of the transcription factor NFκB p50 linked to a peptide cell-permeabilization sequence, the hydrophobic region (h-region) of the signal peptide of Kaposi fibroblast growth factor (K-FGF). SN50 Peptide inhibits translocation of the NF-κB active complex into the nucleus. |
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