| Identification | Back Directory | [Name]
WYC-209 | [CAS]
2131803-90-0 | [Synonyms]
WYC-209
5-Pyrimidinecarboxylic acid, 2-[2-(3,4-dihydro-4,4-dimethyl-1-oxido-2H-1-benzothiopyran-6-yl)ethynyl]-, ethyl ester | [Molecular Formula]
C20H20N2O3S | [MOL File]
2131803-90-0.mol | [Molecular Weight]
368.45 |
| Chemical Properties | Back Directory | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : 83.33 mg/mL (226.16 mM);Water : < 0.1 mg/mL (insoluble) | [form ]
Solid | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
WYC-209 RAR Agonist is used in the preparation of the retinoid compounds and their application as anticancer agents. | [Biological Activity]
Synthetic retinoid with antiproliferative activity''WYC-209 is a synthetic retinoid with antiproliferative activity and better inhibition of cancer cell growth and proliferation than Tazarotene or ATRA (all-trans-retinoic acid). WYC-209 was shown to inhibit proliferation of malignant murine melanoma tumor-repopulating cells (TRCs) with an IC50 value of 190 nM and also inhibited proliferation of TRCs of human melanomalung cancerovarian cancerand breast cancer in culture. |
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| Company Name: |
InvivoChem
|
| Tel: |
13549236410 |
| Website: |
https://www.invivochem.cn/ |
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