| Identification | Back Directory | [Name]
4-(5-ETHOXY-3-PYRIDINYL)-N-METHYL-(3E)-3-BUTEN-1-AMINE DIFUMARATE | [CAS]
212332-35-9 | [Synonyms]
TC 2559 DIFUMARATE
TC 2559 (fumarate)
4-(5-ETHOXY-3-PYRIDINYL)-N-METHYL-(3E)-3-BUTEN-1-AMINE DIFUMARATE | [Molecular Formula]
C20H26N2O9 | [MDL Number]
MFCD09971129 | [MOL File]
212332-35-9.mol |
| Hazard Information | Back Directory | [Biological Activity]
Subtype-selective partial agonist for α 4 β 2 nicotinic acetylcholine receptors (EC 50 values are 0.18, 12.5, 14.0, > 30, > 100 and > 100 μ M for α 4 β 2, α 4 β 4, α 2 β 4, α 3 β 4, α 3 β 2 and α 7 receptor subtypes respectively). Displays selectivity for ( α 4) 2 ( β 2) 3 receptor stoichiometry and enhanced CNS-PNS selectivity ratio. Attenuates scopolamine-induced cognitive deficits in a step-through passive avoidance task. |
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