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Teclistamab is indicated for the treatment of adults with relapsed and refractory multiple myeloma. | [in vivo]
Teclistamab (i.v., 0.1-1 μg, once every 2 days) has anti-tumor activity at high doses in female NSG (NOD/SCID/γc / ) mice with H929 cells model[1].
Animal Model: | Female NSG mice infected with H929 cell lines[1] | Dosage: | 0.1 μg (0.005 mg/kg), 0.5 μg (0.025 mg/kg), or 1 μg (0.05 mg/kg) | Administration: | i.v., on days 0, 3, 5, 7, and 10 | Result: | Completely inhibited tumor growth at doses of 0.5 and 1 μg, while no inhibition of tumor growth was observed at a dose of 0.1 μg. |
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Company Name: |
Biolab Reagents Gold
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Tel: |
027-65279366 18108604356 |
Website: |
www.biolabreagent.com/ |
Company Name: |
Shanghai URChem Limited
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Tel: |
+86-021-50890968,021-50891159 +86-18601776121 |
Website: |
http://www.urchem.com |
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