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ChemicalBook--->CAS DataBase List--->2101206-92-0

2101206-92-0

2101206-92-0 Structure

2101206-92-0 Structure
IdentificationBack Directory
[Name]

2,5-Dioxopyrrolidin-1-yl 17-oxo-4,7,10,13,19-pentaoxa-16-azadocos-21-yn-1-oate
[CAS]

2101206-92-0
[Synonyms]

Propargyl-O-C1-amido-PEG4-C2-NHS ester
2,5-Dioxopyrrolidin-1-yl 17-oxo-4,7,10,13,19-pentaoxa-16-azadocos-21-yn-1-oate
[Molecular Formula]

C20H30N2O10
[MDL Number]

MFCD28898687
[MOL File]

2101206-92-0.mol
[Molecular Weight]

458.46
Chemical PropertiesBack Directory
[density ]

1.26±0.1 g/cm3(Predicted)
[form ]

Liquid
[pka]

13.94±0.46(Predicted)
[color ]

Colorless to light yellow
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P305+P351+P338
Hazard InformationBack Directory
[Uses]

Propargyl-O-C1-amido-PEG4-C2-NHS ester is a nonclaevable 4-unit PEG linker for antibody-agent-conjugation (ADC). Propargyl-O-C1-amido-PEG4-C2-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
[IC 50]

Non-cleavable Linker
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