| Identification | Back Directory | [Name]
N4-Benzoyl-2'-O-propargyladenosine | [CAS]
210096-44-9 | [Synonyms]
N4-Benzoyl-2'-O-propargyladenosine
N6-Benzoyl-2’-O-(2-propyn-1-yl)adenosine
Adenosine, N-benzoyl-2'-O-2-propyn-1-yl-
2'-O-(1-propyn-3-yl)-6-N-benzoyladenosine | [Molecular Formula]
C20H19N5O5 | [MDL Number]
MFCD28976144 | [MOL File]
210096-44-9.mol | [Molecular Weight]
409.4 |
| Hazard Information | Back Directory | [Uses]
N-Benzoyl-2′-O-2-propyn-1-yladenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1]. N-Benzoyl-2′-O-2-propyn-1-yladenosine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | [References]
[1] Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500. DOI:10.1016/j.drudis.2021.02.020 |
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