| Identification | Back Directory | [Name]
Prostaglandin E1 Impurity 4 | [CAS]
21003-46-3 | [Synonyms]
8-Iso-PGE1
OVINONIC ACID
(-)-8-epi-PGE1
8-Epiprostaglandin E1
8-epi-Prostaglandin E1
8-ISO PROSTAGLANDIN E1
Alprostadil EP Impurity F
GMVPRGQOIOIIMI-JCPCGATGSA-N
Prostaglandin (Alprostadil) EP Impurity F
9-oxo-11α,15S-dihydroxy-(8β)-prost-13E-en-1-oic acid
(8β,13E,15S)-11α,15-Dihydroxy-9-oxoprost-13-en-1-oic acid
9-Oxo-11aloha,15S-dihydroxy-(8beta)-prost-13E-en-1-oic acid
9-OXO-11ALPHA,15S-DIHYDROXY-(8BETA)-PROST-13E-EN-1-OIC ACID
Prost-13-en-1-oic acid, 11,15-dihydroxy-9-oxo-, (8β,11α,13E,15S)-
7-[(1S,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]heptanoic acid
f.7-[(1S,2R,3R)-3-hydroxy-2-[(1e,3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]heptanoicacid(8-epiprostaglandine1), | [Molecular Formula]
C20H34O5 | [MDL Number]
MFCD00065736 | [MOL File]
21003-46-3.mol | [Molecular Weight]
354.48 |
| Chemical Properties | Back Directory | [storage temp. ]
Store at -20°C | [solubility ]
DMF: >100 mg/ml (from PGE1); DMSO: >50 mg/ml (from PGE1); Ethanol: >50 mg/ml (from PGE1); PBS pH 7.2: >1.6 mg/ml (from PGE1) | [form ]
A light yellow crystalline solid |
| Hazard Information | Back Directory | [Description]
Isoprostanes are a family of prostanoid molecules of non-cyclooxygenase origin. 8-iso Prostaglandin E1 (8-iso PGE1) is an isoprostane which is found in human semen at levels of 7 μg/ml. It is a pulmonary vasoconstrictor in anesthetized dogs with a potency similar to PGF2α. | [Uses]
8-Isoprostaglandin E1 has vasodilatory and electrophysiological actions porcine coronary artery. It also inhibits acetylcholine release from parasympathetic nerves innervating guinea-pig trachea mediation by prostanoid EP3 receptors. | [Uses]
Isoprostanes are a family of prostanoid molecules of non-cyclooxygenase origin. 8-iso Prostaglandin E1 (8-iso PGE1) is an isoprostane which is found in human semen at levels of 7 μg/ml. It is a pulmonary vasoconstrictor in anesthetized dogs with a potency similar to PGF2α.[Cayman Chemical] | [Definition]
ChEBI:8-Isoprostaglandin E1 is a prostanoid. | [storage]
Store at -20°C |
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