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ChemicalBook--->CAS DataBase List--->2097130-84-0

2097130-84-0

2097130-84-0 Structure

2097130-84-0 Structure
IdentificationBack Directory
[Name]

9(R)-PAHSA
[CAS]

2097130-84-0
[Synonyms]

9(R)-PAHSA
[Molecular Formula]

C34H66O4
[MOL File]

2097130-84-0.mol
[Molecular Weight]

538.89
Chemical PropertiesBack Directory
[Boiling point ]

619.2±38.0 °C(Predicted)
[density ]

0.916±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMF: 20 mg/ml; DMSO: 15 mg/ml; Ethanol: 20 mg/ml; Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml
[pka]

4.78±0.10(Predicted)
Safety DataBack Directory
[Symbol(GHS) ]


GHS02,GHS07
[Signal word ]

Danger
[Hazard statements ]

H225-H319-H336
[Precautionary statements ]

P210-P240-P241-P242-P243-P261-P264-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P312-P337+P313-P370+P378-P403+P233-P403+P235-P405-P501
Hazard InformationBack Directory
[Description]

9(R)-PAHSA is a stereoisomer of 9-PAHSA , an endogenous lipid that belongs to a collection of branched fatty acid esters of hydroxy fatty acids (FAHFAs).1 9-PAHSA is a FAHFA in which palmitic acid is esterified to 9-hydroxy stearic acid. 9(R)-PAHSA is the predominant form that accumulates in adipose tissues in AG4OX mice, which overexpress Glut4 specifically in adipose tissue.2 Also, cell lines favor the production of 9(R)-PAHSA, and carboxyl ester lipase selectively hydrolyzes 9(S)-PAHSA .

The use of this optically-active FAHFA product (the “Product”) is covered by U.S. Patent No. 10,240,025 and corresponding foreign counterpart applications. These patents and applications are licensed by Cayman pursuant to an agreement with BT Food, Drug and Personal Care, LLC, and this Product is sold exclusively for research and development purposes only. Product may not be used for human studies, veterinary use or diagnostics, clinical trial work, clinical diagnostics, or any other clinical trial or approval activities related to humans or animals. This limited label license does not grant any right to use the Product or a Product derivative in commercial products or services. This Product may not be re-sold, distributed, or repackaged unless by official Cayman distributors. For information on commercial rights, please contact the outlicensing department at jforest@biosynthetic.com.
[Uses]

9(R)-PAHSA is a R-enantiomer of 9-PAHSA. 9-PAHSA is an orally available anti-inflammatory lipid that lowers blood sugar and reduces inflammation[1][2].
[References]

1. Yore, M.M., Syed, I., Moraes-Vieira, P.M., et al. Discovery of a class of endogenous mammalian lipids with anti-diabetic and anti-inflammatory effects Cell 159(2),318-332(2014).
2. Nelson, A.T., Kolar, M.J., Chu, Q., et al. Stereochemistry of endogenous palmitic acid ester of 9-hydroxystearic acid and relevance of absolute configuration to regulation J. Am. Chem. Soc. 139(13),4943-4947(2017).
2097130-84-0 suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000 , +1-00000000000
Website: https://www.targetmol.com/
Company Name: Shanghai Hongye Biotechnology Co. Ltd  
Tel: 400-9205774
Website: www.glpbio.cn
Company Name: Shanghai Yifei Biotechnology Co. , Ltd.  
Tel: 021-65675885 18964387627
Website: http://www.efebio.com
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Website: https://www.targetmol.cn/
Company Name: Cayman Chemical Company  
Tel: 800-364-9897
Website: www.caymanchem.com
Company Name: Neobioscience Co., Ltd.  
Tel: 4006-800-892
Website: www.nbs-bio.com
Company Name: Cayman Chemical Company  
Tel: (800) 364-9897
Website: www.caymanchem.com
Company Name: Shanghai Hao Zhun Biological Technology Co., Ltd.  
Tel: 15800340161
Website: www.zzsrm.com
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