| Identification | Back Directory | [Name]
PF-3893787 hydrochloride | [CAS]
2096455-90-0 | [Synonyms]
PF-3893787 hydrochloride
Adriforant hydrochloride | [Molecular Formula]
C13H25ClN6O | [MDL Number]
MFCD31630832 | [MOL File]
2096455-90-0.mol | [Molecular Weight]
316.83 |
| Hazard Information | Back Directory | [Biological Activity]
Adriforant hydrochloride (PF-3893787 hydrochloride) is a novel histamine H4 receptor affinity antagonist (Ki=2.4 nM) and a functional H4 receptor antagonist (Ki=1.56 nM). | [in vitro]
Adriforant is tested and observed binding K i =2.4 nM and functional K i =1.56 nM for H4R. Data from functional assays produce convergent projections of the free plasma efficacious concentration and Adriforant (Compound 13) is fast on/fast off on rhH4R. | [target]
Ki: 2.4 nM (H4R bind), 1.56 nM (H4R func) | [storage]
Store at -20°C |
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| Company Name: |
BOC Sciences
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| Tel: |
1-631-485-4226; 16314854226 |
| Website: |
https://www.bocsci.com |
| Company Name: |
MedChemExpress
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| Tel: |
021-58955995 |
| Website: |
www.medchemexpress.com |
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