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ChemicalBook--->CAS DataBase List--->2095432-71-4

2095432-71-4

2095432-71-4 Structure

2095432-71-4 Structure
IdentificationBack Directory
[Name]

GSK269962 Hydrochloride
[CAS]

2095432-71-4
[Synonyms]

GSK269962 Hydrochloride
[Molecular Formula]

C29H31ClN8O5
[MOL File]

2095432-71-4.mol
[Molecular Weight]

607.07
Chemical PropertiesBack Directory
[storage temp. ]

Inert atmosphere,2-8°C
[solubility ]

DMSO: 100 mg/mL (164.73 mM);Ethanol: 28 mg/mL (46.12 mM)
[Water Solubility ]

Water: Insoluble
Hazard InformationBack Directory
[Biological Activity]

GSK269962A HCl is a selective ROCK (Rho-associated protein kinase) inhibitor with IC50 of 1.6 nM and 4 nM for ROCK1 and ROCK2, respectively.
[target]

< td style="border-bottom: 1px dotted #ccc;padding: 5px;"> MSK1
(Cell-free assay)
TargetValue
ROCK1
(Cell-free assay)		 1.6 nM
ROCK2
(Cell-free assay)		 4 nM
49 nM
RSK1
(Cell-free assay)		 132 nM
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