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ChemicalBook--->CAS DataBase List--->2093386-51-5

2093386-51-5

2093386-51-5 Structure

2093386-51-5 Structure
IdentificationBack Directory
[Name]

Thalidomide-NH-C6-NH2 TFA
[CAS]

2093386-51-5
[Synonyms]

Thalidomide-NH-C6-NH2 TFA
Pomalidomide Related Compound 11 Triflate
4-((6-Aminohexyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione 2,2,2-trifluoroacetate
[Molecular Formula]

C21H25F3N4O6
[MDL Number]

MFCD32690101
[MOL File]

2093386-51-5.mol
[Molecular Weight]

486.45
Chemical PropertiesBack Directory
[solubility ]

Soluble in DMSO
[form ]

Solid
[color ]

Light yellow to yellow
Hazard InformationBack Directory
[Biological Activity]

Thalidomide-NH-C6-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1].
[References]

[1]. Wang Z, et al. Proteolysis Targeting Chimeras for the Selective Degradation of Mcl-1/Bcl-2 Derived from Nonselective Target Binding Ligands. J Med Chem. 2019 Sep 12;62(17):8152-8163.
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