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ChemicalBook--->CAS DataBase List--->209253-80-5

209253-80-5

209253-80-5 Structure

209253-80-5 Structure
IdentificationBack Directory
[Name]

6-B-HYDROXY EPLERENONE
[CAS]

209253-80-5
[Synonyms]

6--Hydroxy Eplerenone
6β-Hydroxy Eplerenone
Eplerenone Impurity 11
6-B-HYDROXY EPLERENONE
6-beta-Hydroxy Eplerenone
Eplerenone 6-β-Hydroxy Analog
Eplerenone 6-beta-Hydroxy Analog
(6β,7α,11α,17α)-9,11-Epoxy-6,17-dihydroxy-3-oxo-pregn-4-ene-7,21-dicarboxylic Acid γ-Lactone Methyl Ester
Pregn-4-ene-7,21-dicarboxylic acid, 9,11-epoxy-6,17-dihydroxy-3-oxo-, γ-lactone, methyl ester, (6β,7α,11α,17α)-
[Molecular Formula]

C24H30O7
[MOL File]

209253-80-5.mol
[Molecular Weight]

430.49
Chemical PropertiesBack Directory
[Melting point ]

128-135°C
[Boiling point ]

642.7±55.0 °C(Predicted)
[density ]

1.37±0.1 g/cm3(Predicted)
[storage temp. ]

-20°C Freezer
[solubility ]

Chloroform (Slightly), Methanol (Slightly)
[form ]

Solid
[pka]

13.16±0.70(Predicted)
[color ]

White to Off-White
Hazard InformationBack Directory
[Description]

6β-hydroxy Eplerenone is a major metabolite of the mineralocorticoid receptor antagonist eplerenone . It is formed from eplerenone by the cytochrome P450 (CYP) isoform CYP3A4.
[Chemical Properties]

White to Off-White Solid
[Uses]

6-B-HYDROXY EPLERENONE is a metabolite of Eplerenone, which is used alone or in combination with other medications to treat high blood pressure. 6-B-HYDROXY EPLERENONE is in a class of medications called mineralocorticoid receptor antagonists. It works by blocking the action of aldosterone, a natural substance in the body that raises blood pressure.
[Uses]

A metabolite of Eplerenone, which is used alone or in combination with other medications to treat high blood pressure. Eplerenone is in a class of medications called mineralocorticoid receptor antagonists. It works by blocking the action of aldosterone, a natural substance in the body that raises blood pressure.
[storage]

Store at -20°C
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