| Identification | Back Directory | [Name]
2-Chloro-N-(6-methoxy-4-quinolinyl)-5-nitrobenzamide | [CAS]
2088135-12-8 | [Synonyms]
SR 16832
2-Chloro-N-(6-methoxy-4-quinolinyl)-5-nitrobenzamide
2-Chloro-N-(6-methoxyquinolin-4-yl)-5-nitrobenzamide
Benzamide, 2-chloro-N-(6-methoxy-4-quinolinyl)-5-nitro- | [Molecular Formula]
C17H12ClN3O4 | [MDL Number]
MFCD31656711 | [MOL File]
2088135-12-8.mol | [Molecular Weight]
357.75 |
| Chemical Properties | Back Directory | [Boiling point ]
492.3±45.0 °C(Predicted) | [density ]
1.469±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO: soluble | [form ]
A crystalline solid | [pka]
9.71±0.43(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
SR 16832 is a dual site PPARγ inhibitor. Acts at orthosteric and allosteric sites in the ligand binding domain. Inhibits binding of endogenous ligands and transcriptional activity of PPARγ, more effectively than the orthosteric covalent antagonists. | [Biological Activity]
SR16832 is a PPARγ antagonist. It acts as a dual-site covalent inhibitor of PPARγ inhibiting both orthosteric and allosteric cellular activation by the PPARγ agonists. | [storage]
Store at +4°C |
|
| Company Name: |
DC Chemicals
|
| Tel: |
021-58447131 13564518121 |
| Website: |
http://m.is0513.com/ShowSupplierProductsList927327/0.htm |
|