| Identification | Back Directory | [Name]
epothilone F | [CAS]
208518-52-9 | [Synonyms]
CS-1032
epothilone F
epothilone F USP/EP/BP
Ixabepilone Impurity 8 (Epothilone F)
(1S,3S(E),7S,10R,11S,12S,16R)-7,11-dihydroxy-3-[2-(2-hydroxymethyl-thiazol-4-yl)-1-methyl-vinyl]-8,8,10,12,16-pentamethyl-4,17-dioxa-bicyclo[14.1.0]heptadecane-5,9-dione
4,17-Dioxabicyclo[14.1.0]heptadecane-5,9-dione, 7,11-dihydroxy-3-[(1E)-2-[2-(hydroxymethyl)-4-thiazolyl]-1-methylethenyl]-8,8,10,12,16-pentamethyl-, (1S,3S,7S,10R,11S,12S,16R)- | [Molecular Formula]
C27H41NO7S | [MDL Number]
MFCD19982658 | [MOL File]
208518-52-9.mol | [Molecular Weight]
523.68 |
| Chemical Properties | Back Directory | [Boiling point ]
711.3±60.0 °C(Predicted) | [density ]
1.179±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
13.15±0.10(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
Epothilone F is a related compound of Epothilones, which are a novel class of antineoplastic agents with antitubulin activity. In addition, Epothilones utilize a similar mechanism of action to that of taxanes and are less susceptible to multidrug resistance caused by P-glycoprotein. Studies showed that Epothilones exhibit antitumor activity against human cancer cells that are taxane-resistant. |
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DC Chemicals
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cjbscvictory
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