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ChemicalBook--->CAS DataBase List--->2074607-48-8

2074607-48-8

2074607-48-8 Structure

2074607-48-8 Structure
IdentificationBack Directory
[Name]

IWP-O1
[CAS]

2074607-48-8
[Synonyms]

IWP-O1
IWO-O1
IWP-O1(17)
IWP-O1 >=98% (HPLC)
1H-1,2,3-Triazole-1-acetamide, 5-phenyl-N-(5-phenyl-2-pyridinyl)-4-(4-pyridinyl)-
[Molecular Formula]

C26H20N6O
[MOL File]

2074607-48-8.mol
[Molecular Weight]

432.48
Chemical PropertiesBack Directory
[storage temp. ]

Keep in dark place,Sealed in dry,2-8°C
[solubility ]

DMSO : 125 mg/mL (289.03 mM);Water : < 0.1 mg/mL (insoluble)
[form ]

Solid
[color ]

Light yellow to yellow
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P305+P351+P338
Spectrum DetailBack Directory
[Spectrum Detail]

IWP-O1(2074607-48-8)1HNMR
Hazard InformationBack Directory
[Biological Activity]

IWP-O1 is a porcn inhibitor with an EC50 of 80 pM in a Wnt signaling reporter assay in cultured cells. It can effectively inhibit the phosphorylation of Dvl2/3 in Hela cells.
[in vitro]

IWP-O1 has good metabolic stability.

[target]

TargetValue
porcn
(Cell-based assay)		 80 pM(EC50)
[storage]

4°C, protect from light
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