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ChemicalBook--->CAS DataBase List--->2070015-09-5

2070015-09-5

2070015-09-5 Structure

2070015-09-5 Structure
IdentificationBack Directory
[Name]

NU6300
[CAS]

2070015-09-5
[Synonyms]

NU6300
NU 6300;NU6300
9H-Purin-2-amine, 6-(cyclohexylmethoxy)-N-[4-(ethenylsulfonyl)phenyl]-
[Molecular Formula]

C20H23N5O3S
[MOL File]

2070015-09-5.mol
[Molecular Weight]

413.49
Chemical PropertiesBack Directory
[Boiling point ]

730.8±70.0 °C(Predicted)
[density ]

1.344±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMSO : ≥ 32 mg/mL (77.39 mM)
[form ]

Solid
[pka]

9.33±0.10(Predicted)
[color ]

White to off-white
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P280-P301+P312-P302+P352-P305+P351+P338
Hazard InformationBack Directory
[Uses]

NU6300 is a covalent, irreversible and ATP-competitive CDK2 inhibitor with an IC50 value of 0.16 μM. NU6300 can be used for the research of eukaryotic cell cycle- and transcription-related[1].
[IC 50]

CDK2
[storage]

Store at -20°C
[References]

[1] Anscombe E, et al. Identification and Characterization of an Irreversible Inhibitor of CDK2. Chem Biol. 2015 Sep 17;22(9):1159-1164. DOI:10.1016/j.chembiol.2015.07.018
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