Identification | Back Directory | [Name]
4-Methylumbelliferylb-D-galactopyranoside-6-sulphatesodiumsalt | [CAS]
206443-06-3 | [Synonyms]
4-Methyl-7-[(6-O-sulfo-β-D-galactopyranosyl)oxy]- 4-Methylumbelliferylb-D-galactopyranoside-6-sulphatesodiumsalt 4-Methylumbelliferyl β-D-Galactopyranoside-6-sulfate Sodium Salt 4-Methylumbelliferyl β-D-Galactopyranoside-6-sulfate sodium salt 4-Methylumbelliferyl β-D-galactopyranoside-6-sulphate sodium salt 4-Methylumbelliferyl β-D-galactopyranoside-6-sulphate sodium salt [(3R,4S,5S,6S)-3,4,5-trihydroxy-6-(4-methyl-2-oxochromen-7-yl)oxyoxan-2-yl]methyl sulfate 4-Methyl-7-[(6-O-sulfo-beta-D-galactopyranosyl)oxy]-2H-1-benzopyran-2-one monosodium salt [(3R,4S,5S,6S)-3,4,5-trihydroxy-6-(4-methyl-2-oxo-chromen-7-yl)oxy-tetrahydropyran-2-yl]methoxysulfonyloxysodium | [EINECS(EC#)]
1533716-785-6 | [Molecular Formula]
C16H17NaO11S | [MDL Number]
MFCD01861961 | [MOL File]
206443-06-3.mol | [Molecular Weight]
440.354 |
Chemical Properties | Back Directory | [Melting point ]
196-198?C | [storage temp. ]
-20°C Freezer, Under Inert Atmosphere | [solubility ]
Methanol (Slightly, Sonicated), Water (Slightly) | [form ]
Solid | [color ]
White to Off-White | [Stability:]
-20?C Freezer, Under Inert Atmosphere |
Hazard Information | Back Directory | [Description]
4-Methylumbelliferyl β-D-Galactopyranoside-6-sulfate (sodium salt) (4-MU-Gal-6S) is a fluorogenic substrate used to quantify N-acetylgalactosamine-6-sulphatase (GALNS) activity. 4-MU-Gal-6S is cleaved by GALNS to release the fluorescent moiety 4-MU. 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high (7.12-10.3) pH, respectively, and an emission maximum ranging from 445 to 455 nM, increasing as pH decreases. It has been used to detect Morquio disease type A, a lysosomal storage disorder in which GALNS is deficient. 4-MU-Gal-6S can be used to assess GALNS activity in a very small blood volume to determine the extent of deficiency. | [Chemical Properties]
White Solid | [Uses]
4-Methylumbelliferylb-D-galactopyranoside-6-sulphatesodiumsalt is used for the determination of galactose-6-sulphate sulphatase activity,it is used in the diagnosis of Mucopolysaccharidosis IV A.
| [Uses]
Used for the determination of galactose-6-sulphate sulphatase activity. Used in the diagnosis of Mucopolysaccharidosis IV A. | [storage]
Store at -20°C |
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