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ChemicalBook--->CAS DataBase List--->206055-69-8

206055-69-8

206055-69-8 Structure

206055-69-8 Structure
IdentificationBack Directory
[Name]

2'-O,4'-C-Methylenecytidine
[CAS]

206055-69-8
[Synonyms]

2'-O,4'-C-Methylenecytidine
Cytidine, 2'-O,4'-C-methylene-
2’-O,4’-C-Methylenecytidine, LNA-C
[Molecular Formula]

C10H13N3O5
[MDL Number]

MFCD28342628
[MOL File]

206055-69-8.mol
[Molecular Weight]

255.23
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[form ]

Solid
[color ]

White to off-white
Hazard InformationBack Directory
[Biological Activity]

2'-O,4'-C-Methylenecytidine (LNA-C(Bz)) is a bicyclic nucleoside analogue with fixed N-type conformation. 2'-O,4'-C-Methylenecytidine can be used to synthesize oligonucleotides. 2'-O,4'-C-Methylenecytidine forms duplexes with complementary DNA and RNA strands[1][2].
[References]

[1]. bicyclic nucleoside analogue, N-type conformation, synthesize oligonucleotides, duplexes [2]. Obika S, et, al. Stability and structural features of the duplexes containing nucleoside analogues with a fixed N-type conformation, 2′-O,4′-C-methyleneribonucleosides. Tetrahedron Letters. 1998 Jul 23; 39(30):5401-04.
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