| Identification | Back Directory | [Name]
2-(2-aminoethyl)phenol | [CAS]
2039-66-9 | [Synonyms]
o-TyraMine
RARECHEM AN KA 0080
2-hydrophenethylaMine
2-(2-AMINOETHYL)PHENOL
o-(2-AMinoethyl)phenol
o-HydroxyphenethylaMine
2-(2-azanylethyl)phenol
2-HYDROXYPHENETHYLAMINE
2-(2-Hydroxyphenyl)ethanamine
2-(2-Hydroxyphenyl)ethylaMine
2-(o-Hydroxyphenyl)ethylaMine | [EINECS(EC#)]
218-016-3 | [Molecular Formula]
C8H11NO | [MDL Number]
MFCD00192585 | [MOL File]
2039-66-9.mol | [Molecular Weight]
137.18 |
| Hazard Information | Back Directory | [Uses]
A ortho-hydroxylated phenylethylamine present in urine of patients with affective disorder following (MAO-inhibiting) antidepressant drug treatment. It has been used in studies as a substrate of monoa
mine oxidase B and was revealed to be a potential inactivator of MAO-B. | [Definition]
ChEBI: 2-(2-aminoethyl)phenol is a primary amine. | [Synthesis Reference(s)]
The Journal of Organic Chemistry, 41, p. 2502, 1976 DOI: 10.1021/jo00876a038 |
| Questions and Answers (Q&A) | Back Directory | [Description]
2-Hydroxyphenethylamine (also known as phenylethanolamine) is a kind of trace amine found in the brain. It may modulate the sympathetic functions. It has strong cardiovascular activity, and can be used as a drug to produce topical vasoconstriction. Its derivatives are adrenergic agonists and antagonists, and have the potential for the treatment of respiratory diseases.
| [References]
https://en.wikipedia.org/wiki/Phenylethanolamine
Biggadike, Keith, et al. "PHENYLETHANOLAMINE DERIVATIVES FOR THE TREATMENT OF RESPIRATORY DISEASES." WO, EP 1556340 A1. 2005.
https://pubchem.ncbi.nlm.nih.gov/compound/2-Amino-1-phenylethanol#section=Top
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