| Chemical Properties | Back Directory | [storage temp. ]
−20°C
| [solubility ]
aqueous buffer: soluble
| [form ]
lyophilized powder
| [color ]
White to off-white | [biological source]
(from Hysterocrates gigas (African tarantula)) | [Water Solubility ]
Soluble in water |
| Hazard Information | Back Directory | [Biological Activity]
SNX-482 is a peptidyl toxin originally isolated from the venom of the spider Hysterocrates gigas. SNX-482 specifically blocks Cav2.3 (a1ER-type) calcium channels in a voltage dependent manner. SNX-482 also blocks P/Q-type voltage-gated Ca2+ channels and blocks A-type K+ channels (IC50 of <3 nm). | [storage]
Desiccate at -20°C |
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