| Identification | Back Directory | [Name]
RalfinaMide Mesylate | [CAS]
202825-45-4 | [Synonyms]
CS-1138
RALFINAMIDE MESYLATE
FCE-26742A (mesylate)
(S)-2-((4-((2-fluorobenzyl)oxy)benzyl)aMino)propanaMide Methanesulfonate
(2S)-2-[[[4-[(2-Fluorophenyl)methoxy]phenyl]methyl]amino]-propanamide methanesulfonate | [Molecular Formula]
C18H23FN2O5S | [MDL Number]
MFCD19690932 | [MOL File]
202825-45-4.mol | [Molecular Weight]
398.449 |
| Chemical Properties | Back Directory | [Melting point ]
230-235°C | [storage temp. ]
2-8°C | [solubility ]
H2O: >15mg/mL | [form ]
powder | [color ]
white to beige | [optical activity]
[α]/D 10 to 15° (c=1 HOAc) | [Water Solubility ]
H2O: >15mg/mL |
| Hazard Information | Back Directory | [Uses]
Ralfinamide mesylate is a mixed sodium and N-type calcium channel protein inhibitor. Inhibitory activity of Ralfinamide mesylate is voltage dependent, with higher potency towards inactivated channels.
Ralfinamide mesylate is useful in preventing, alleviating and curing a wide range of pathologies, including pain, migraine, peripheral diseases, cardiovascular diseases, inflammatory processes affect
ing all body systems, disorders affecting skin and related tissues, disorders of the respiratory system, disorders of the immune and endocrinol. systems, gastrointestinal, urogenital, metabolic and se
izure disorders. | [Biological Activity]
Ralfinamide is a mixed sodium and N-type calcium channel blocker. Inhibiton is voltage-dependentwith higher potency against inactivated channels. Ralfinamide is two fold selective for tetrodotoxin (TTX)-resistant sodium channels compared with TTX-sensitive currents. | [storage]
Store at -20°C |
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