| Identification | Back Directory | [Name]
5-Pyrimidinecarboxamide, N-[5-[2-(1-cyano-1-methylethyl)-4-pyridinyl]-4-(trifluoromethyl)-2-thiazolyl]-4,6-dimethoxy- | [CAS]
2019994-90-0 | [Synonyms]
5-Pyrimidinecarboxamide, N-[5-[2-(1-cyano-1-methylethyl)-4-pyridinyl]-4-(trifluoromethyl)-2-thiazolyl]-4,6-dimethoxy- | [Molecular Formula]
C20H17F3N6O3S | [MOL File]
2019994-90-0.mol | [Molecular Weight]
478.45 |
| Chemical Properties | Back Directory | [density ]
1.417±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
DMSO: 2mg/mL, clear | [form ]
powder | [pka]
2.84±0.70(Predicted) | [color ]
white to beige |
| Hazard Information | Back Directory | [Biological Activity]
Trpvicin is a sub-type selective and potent inhibitor of TRPV3. Trpvicin shows efficacy in the inhibition of itch and hair loss in mouse models. It appears th at Trpvicin stabilizes TRPV3 channel in its a closed state. |
|
| Company Name: |
Merck KGaA
|
| Tel: |
(+86) 21 2033 8288 |
| Website: |
http://www.sigmaaldrich.cn |
|