Identification | Back Directory | [Name]
NF-κB Control | [CAS]
201608-17-5 | [Synonyms]
NF-κB Control NF-.kappa.B Control NAOYXUUPTUDXHE-YQTWEEOYSA-N | [Molecular Formula]
C123H215N33O30S | [MOL File]
201608-17-5.mol | [Molecular Weight]
2668.29 |
Chemical Properties | Back Directory | [storage temp. ]
Store at -20°C | [solubility ]
DMF: 25 mg/ml; DMSO: 10 mg/ml; Ethanol: 1 mg/ml; PBS (pH 7.2): 1 mg/ml | [form ]
A crystalline solid |
Hazard Information | Back Directory | [Uses]
NF-κB inhibitor is a synthetic peptide corresponding to the nuclear localization sequence (NLS) of NF-κB p105 subunit (also known as p50) appended to a hydrophobic sequence to facilitate import into living cells. It blocks the nuclear import of p105 in cells treated with activators of NF-κB signaling, including LPS and TNF-α. NF-κB control is a peptide that is identical in sequence to NF-κB inhibitor, except two essential, basic residues of the p105 NLS are substituted with non-basic amino acids. It is ineffective at blocking the activation of NF-κB signaling and is used as a negative control peptide.[Cayman Chemical] | [storage]
Store at -20°C |
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