| Identification | Back Directory | [Name]
Nangibotide | [CAS]
2014384-91-7 | [Synonyms]
Nangibotide
L-Methioninamide, L-leucyl-L-glutaminyl-L-α-glutamyl-L-α-glutamyl-L-α-aspartyl-L-alanylglycyl-L-α-glutamyl-L-tyrosylglycyl-L-cysteinyl- | [Molecular Formula]
C54H82N14O22S2 | [MOL File]
2014384-91-7.mol | [Molecular Weight]
1343.44 |
| Hazard Information | Back Directory | [Uses]
Nangibotide is a TREM-1 receptor inhibitor that can modulate innate immune response. Nangibotide can reduce systemic and in situ inflammatory reaction in rodent models of myocardial ischaemia‐reperfusion[1]. | [References]
[1] Cuvier V, et, al. A first-in-man safety and pharmacokinetics study of nangibotide, a new modulator of innate immune response through TREM-1 receptor inhibition. Br J Clin Pharmacol. 2018 Oct;84(10):2270-2279. DOI:10.1111/bcp.13668 |
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| Company Name: |
Ontores Biotech
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| Tel: |
0571-88760729 18072970094 |
| Website: |
www.ontoresinc.cn |
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