| Identification | Back Directory | [Name]
ER-27319 | [CAS]
201010-95-9 | [Synonyms]
ER 27319 MALEATE
10-(3-AMINOPROPYL)-3,4-DIMETHYL-9(10H)-ACRIDINONE MALEATE | [Molecular Formula]
C22H24N2O5 | [MDL Number]
MFCD08703129 | [MOL File]
201010-95-9.mol | [Molecular Weight]
396.436 |
| Hazard Information | Back Directory | [Uses]
ER 27319 Maleate is a PLK-1 and Syk inhibitor. | [Biological Activity]
Selective inhibitor of Syk kinase. Inhibits tyrosine phosphorylation of Syk initiated by the engagement of Fc ε RI in rat and human mast cells. Results in the abrogation of degranulation, TNF- α production (IC 50 = 10 μ M) and other related signaling events. |
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