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ChemicalBook--->CAS DataBase List--->200880-42-8

200880-42-8

200880-42-8 Structure

200880-42-8 Structure
IdentificationBack Directory
[Name]

1,2-distearoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodiuM salt)
[CAS]

200880-42-8
[Synonyms]

18:0 PG
DSPG Sodium Salt
L-α-Phosphatidyl-DL-glycerol, distearoyl
1,2-Distearoyl-sn-glycero-3-PG (sodium salt)
1,2-Distearoyl-sn-glycero-3-phosphorylglycerol sodium salt
1,2-distearoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodiuM salt)
Sodium (2R)-2,3-Bis(stearoyloxy)propyl 2,3-Dihydroxypropyl Phosphate
1,2-Dioctadecanoyl-sn-glycero-3-phospho-(1′-rac-glycerol) sodium salt
1,2-distearoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodium salt)(DSPG)
sodium [(2R)-2,3-bis(1-oxooctadecoxy)propyl] 2,3-dihydroxypropyl phosphate
1,2-DISTEAROYL-SN-GLYCERO-3-PHOSPHO-(1'-RAC-GLYCEROL) (SODIUM SALT);18:0 PG;DSPG;PG(18:0/18:0)
Octadecanoic acid (1R)-1-[[[(2,3-dihydroxypropoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl ester monosodium salt
1,2-Dioctadecanoyl-sn-glycero-3-phospho-(1′-rac-glycerol) sodium salt, 1,2-Distearoyl-sn-glycero-3-phosphoglycerol, L -α-Phosphatidyl-DL-glycerol, distearoyl, DSPG-Na, Octadecanoic acid (1R)-1-[[[(2,3-dihydroxypropoxy)hydroxyphosphinyl]oxy]methyl]-1,2-eth
[Molecular Formula]

C81H159Na2O16P
[MDL Number]

MFCD00077290
[MOL File]

200880-42-8.mol
[Molecular Weight]

1466.07
Chemical PropertiesBack Directory
[storage temp. ]

-20°C
[solubility ]

Chloroform:Methanol:Water = 2:1:0.1 (Very Slightly)
[form ]

Solid
[color ]

White to Off-White
[Stability:]

Hygroscopic
Safety DataBack Directory
[WGK Germany ]

3
Hazard InformationBack Directory
[Description]

DSPG, also known as 1,2-Distearoyl-sn-glycero-3-phosphoglycerol, is a phospholipid molecule with phosphate polar head connected to two non-polar lipid (stearic acid) by a glycerol molecule. In water, the molecule can orient itself into lipid bilayer and can be used for drug encapsulation, such as drug loaded liposomes or nanoparticles.
[Uses]

1,2-Distearoyl-sn-glycero-3-phospho-rac-(1-glycerol) Sodium Salt is used to prepare polyethyleneglycol-modified liposomal doxorubicin for therapies against drug resistant tumors. It is also used in the PEGylated liposomal drug formulation of the anti-cancer agent oxaliplatin.
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