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ChemicalBook--->CAS DataBase List--->2005454-12-4

2005454-12-4

2005454-12-4 Structure

2005454-12-4 Structure
IdentificationBack Directory
[Name]

PD1 Inhbitor, Aurigene Cmpd 16
[CAS]

2005454-12-4
[Synonyms]

PD1 Inhbitor, Aurigene Cmpd 16
PD1 PDL1 IN 1,PD-1-PDL1-IN 1,PD1PDL1IN 1
[Molecular Formula]

C14H23N7O6
[MDL Number]

MFCD30747874
[MOL File]

2005454-12-4.mol
[Molecular Weight]

385.38
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
Hazard InformationBack Directory
[Description]

PD1-PDL1-IN 1 is a potent programmed cell death 1 (PD-1) inhibitor. PD1-PDL1-IN 1 is useful as immune modulator[1].

PD-1 (or Programmed Cell Death 1 or PDCD1) is a ~55kD type I membrane glycoprotein and is a receptor of the CD28 superfamily that negatively regulates T cell antigen receptor signalling by interacting with the specific ligands. PD-1 is suggested to play significant role in the maintenance of self-tolerance[1].

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