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ChemicalBook--->CAS DataBase List--->199864-86-3

199864-86-3

199864-86-3 Structure

199864-86-3 Structure
IdentificationBack Directory
[Name]

2-PyriMidinaMine, 4-(4-fluoro-1-naphthalenyl)-6-(1-Methylethyl)-, Monohydrochloride
[CAS]

199864-86-3
[Synonyms]

MT 500 Hydrochloride
RS 127445 hydrochloride NEW
4-(4-Fluoro-1-naphthyl)-6-isopropylpyriMidin-2-aMine
2-Amino-4-(4-fluoronaphth-1-yl)-6-isopropylpyrimidine hydrochloride
2-AMino-4-(4-fluoronaphth-1-yl)-6-isopropylpyriMidine Monohydrochloride
4-(4-Fluoro-1-naphthalenyl)-6-(1-methylethyl)-2-pyrimidinamine monohydrochloride
2-PyriMidinaMine, 4-(4-fluoro-1-naphthalenyl)-6-(1-Methylethyl)-, Monohydrochloride
[Molecular Formula]

C17H17ClFN3
[MDL Number]

MFCD11112196
[MOL File]

199864-86-3.mol
[Molecular Weight]

317.788
Chemical PropertiesBack Directory
[Melting point ]

158 °C
[storage temp. ]

2-8°C
[solubility ]

DMSO: ≥20mg/mL
[form ]

powder
[color ]

white to tan
Safety DataBack Directory
[Hazard Codes ]

T
[Risk Statements ]

25-36
[Safety Statements ]

26-45
[RIDADR ]

UN 2811 6.1 / PGIII
[WGK Germany ]

3
[HS Code ]

2933.59.5300
Hazard InformationBack Directory
[Uses]

RS-127445 is a selective; high affinity; orally bioavailable serotonin 5-HT2B receptor antagonist. RS-127445 was found to have nanomolar affinity for the 5-HT2B receptor (pKi=9.5) and 1,000 fold selec tivity for this receptor as compared to numerous other receptor and ion channel binding sites.
[Biological Activity]

RS-127445 is a selective; high affinity; orally bioavailable serotonin 5-HT2B receptor antagonist. RS-127445 was found to have nanomolar affinity for the 5-HT2B receptor (pKi=9.5) and 1,000 fold selectivity for this receptor as compared to numerous other receptor and ion channel binding sites.
[storage]

Desiccate at +4°C
Spectrum DetailBack Directory
[Spectrum Detail]

2-PyriMidinaMine, 4-(4-fluoro-1-naphthalenyl)-6-(1-Methylethyl)-, Monohydrochloride(199864-86-3)1HNMR
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