| Hazard Information | Back Directory | [Description]
MMSET-IN-1 is a multiple myeloma SET domain (MMSET, aka NSD2/WHSC1) inhibitor against SETD2 and MMSET with IC50s of 0.49 and 3.3 μM, respectively. MMSET-IN-1 has a Kd of 1.6 μM for MMSET[1].
IC50: 0.49 μM (SETD2), 3.3 μM (MMSET)[1]Kd: 1.6 μM[1] | [storage]
Store at -20°C | [References]
[1]. Tisi D, et al. Structure of the Epigenetic Oncogene MMSET and Inhibition by N-Alkyl Sinefungin Derivatives. ACS Chem Biol. 2016 Nov 18;11(11):3093-3105. |
|
|