Identification | Back Directory | [Name]
3-Pyridinol, 2,6-bis(2-amino-4-pyrimidinyl)- | [CAS]
1983983-41-0 | [Synonyms]
BEY1107 Avotaciclib 3-Pyridinol, 2,6-bis(2-amino-4-pyrimidinyl)- | [Molecular Formula]
C13H11N7O | [MOL File]
1983983-41-0.mol | [Molecular Weight]
281.27 |
Chemical Properties | Back Directory | [Boiling point ]
740.0±70.0 °C(Predicted) | [density ]
1.487±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [form ]
Solid | [pka]
3.67±0.10(Predicted) | [color ]
Light yellow to yellow |
Hazard Information | Back Directory | [Uses]
Avotaciclib (BEY1107) is a potent and orally active inhibitor of cyclin dependent kinase 1 (CDK1). Avotaciclib can be used for the research of locally advanced or metastatic pancreatic cancer[1]. | [IC 50]
CDK1 | [storage]
Store at -20°C | [References]
[1] Seufferlein T, et, al. Phase I Trials in Pancreatic Cancer. Translational Pancreatic Cancer Research pp 219-232. |
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