Identification | Back Directory | [Name]
LGWCOUWMTAQMQT-QCBHMXSDSA-N | [CAS]
196493-76-2 | [Synonyms]
LGWCOUWMTAQMQT-QCBHMXSDSA-N 2H-Pyran-3-pentanoic acid, tetrahydro-4,6-dihydroxy-2-[(1E,3S)-3-hydroxy-1-octen-1-yl]-, (2R,3S,4S)- | [Molecular Formula]
C18H32O6 | [MOL File]
196493-76-2.mol | [Molecular Weight]
344.44 |
Chemical Properties | Back Directory | [Boiling point ]
559.6±50.0 °C(Predicted) | [density ]
1.189±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMF: 50 mg/ml; DMSO: 20 mg/ml; Ethanol: 50 mg/ml; PBS (pH 7.2): .15 mg/ml | [pka]
4.76±0.10(Predicted) |
Hazard Information | Back Directory | [Description]
Thromboxane B2 (TXB2) is released in substantial quantities from aggregating platelets and metabolized during circulation to 11-dehydro TXB2 and 2,3-dinor TXB2. In rats and rabbits, 2,3-dinor TXB1 has been identified as another urinary metabolite of TXB2. However in human urine, only trace amounts of 2,3-dinor TXB1 have been identified. In rats, 2,3-dinor TXB1 is excreted at a much higher rate than 2,3-dinor TXB2 (19.2 ± 4.9 ng/24 hr and 1.6 ± 0.3 ng/24 hr, respectively). Therefore, urinary 2,3-dinor TXB1 is a suitable marker of thromboxane biosynthesis in rats. |
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