| Identification | Back Directory | [Name]
2',7'-DIFLUOROFLUORESCEIN | [CAS]
195136-58-4 | [Synonyms]
OREGON GREEN(TM) 488
2',7'-DIFLUOROFLUORESCEIN
2',7'-Difluoro-3',6'-dihydroxy-3H-spiro[isobenzofuran-1,9'-xanthen]-3-one
2',7'-Difluoro-3',6'-dihydroxyspiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one
Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 2',7'-difluoro-3',6'-dihydroxy- | [Molecular Formula]
C20H10F2O5 | [MDL Number]
MFCD01311849 | [MOL File]
195136-58-4.mol | [Molecular Weight]
368.29 |
| Chemical Properties | Back Directory | [Boiling point ]
591.7±50.0 °C(Predicted) | [density ]
1.70±0.1 g/cm3(Predicted) | [solubility ]
Insoluble in water; soluble in N,Ndimethylformamide | [form ]
A solid | [pka]
4.8, (at 22℃);4.7, (at 22℃) | [color ]
Orange powder | [λmax]
490 nm (Buffer pH 9.0) | [Biological Applications]
Detecting atherosclerosis;detecting/monitoring amyloid Aβ
production/accumulation/aggregation/disaggregation;
diagnosing Alzheimer’s disease;estimating/measuring
concentration of cortisol, melatonin, secretory
IgA in body fluids;11 evaluating cetuximab-based
imaging probe to target epidermal growth factor
receptor (EGFR);examining biodistribution of
proteins;investigating/measuring protein-protein
and protein-nucleic acid interactions;measuring
pH of apoplast at the root surface;visualizing hair
follicles;as a substrate for measuring β-lactamase
activity,phosphatases activity | [Major Application]
As geothermal tracers;TiO2
nanoparticles for light energy conversion |
| Hazard Information | Back Directory | [Uses]
2'',7''-Difluorofluorescein is a reactant used in the synthesis of biarsenical probes that inhibit protein tyrosine phosphatases. |
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