Identification | Back Directory | [Name]
2-(4-TERT-BUTYLPHENOXY)CYCLOHEXANOL | [CAS]
1942-71-8 | [Synonyms]
propargite metab. 2-(p-t-butylphenoxy)cyclohexanol 2-(p-tert-butylphenoxy)-cyclohexano 2-(4-TERT-BUTYLPHENOXY)CYCLOHEXANOL CYCLOHEXANOL-2-(4-TERT-BUTYL-PHENOXY) 2-(4-tert-butylphenoxy)cyclohexan-1-ol 2-(4-tert-butylphenoxy)-1-cyclohexanol 2-[4-(1,1-DIMETHYLETHYL)PHENOXY]CYCLOHEXANOL Cyclohexanol, 2-[4-(1,1-dimethylethyl)phenoxy]- | [EINECS(EC#)]
217-732-3 | [Molecular Formula]
C16H24O2 | [MDL Number]
MFCD00155433 | [MOL File]
1942-71-8.mol | [Molecular Weight]
248.36 |
Hazard Information | Back Directory | [Biological Activity]
tBPC is a postitive allosteric modulator of the neuropeptide Y (NPY) Y4 receptorwhich is predominantly expressed in the gastrointestinal tract and activated most strongly by pancreatic polypeptide (PP). tBPC was shown to potentiate Y4R activity in G-Protein signaling and arrestin3 recruitment and to potentiate the native PP response. tBPC was selective for Y4R over other Neuropeptide Y receptors and showed no effect on the efficacy (Emax) or potency (EC50) of the NPY signal response at the Y1Y2or Y5 receptors at 30 μM. |
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