| Identification | Back Directory | [Name]
1-(4-Aminophenyl)-4-methyl-7,8-methylenedioxy-5H-2,3-benzodiazepine hydrochloride | [CAS]
192065-56-8 | [Synonyms]
GYKI 52466 (HCl salt)
GYKI 52466 hydrochloride solid
1-(4-AMINOPHENYL)-4-METHYL-7,8-METHYLENEDIOXY-5H-2,3-BENZODIAZEPINE HYDROCHLORIDE
4-(8-Methyl-9H-[1,3]dioxolo[4',5':4,5]benzo[1,2-d][1,2]diazepin-5-yl)aniline hydrochloride
4-(8-Methyl-9H-[1,3]dioxolo[4',5':4,5]benzo[1,2-d][1,2]diazepin-5-yl)aniline hydrochloride
Benzenamine, 4-(8-methyl-9H-1,3-dioxolo[4,5-h][2,3]benzodiazepin-5-yl)-, hydrochloride (1:1)
GYKI 52466 hydrochloride,1-(4-Aminophenyl)-4-methyl-7,8-methylenedioxy-5H-2,3-benzodiazepine hydrochloride | [Molecular Formula]
C17H15N3O2HCl | [MDL Number]
MFCD00153803 | [MOL File]
192065-56-8.mol | [Molecular Weight]
329.78 |
| Hazard Information | Back Directory | [Uses]
GYKI 52466 hydrochloride has been used as an α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor selective antagonist in cell viability assays to evaluate the specificity of kainate (KA) effect on cerebellar granule cells (CGCs). It has also been used as an AMPA blocker to study the function of glutamate in neuroadapted sindbis virus (NSV) -induced motor neuron death. | [Biochem/physiol Actions]
GYKI 52466 serves as an antagonist of several processes, mediated by glutamate. |
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Merck KGaA
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