| Identification | Back Directory | [Name]
JAK3i
(JAK3 inhibitor JAK3i) | [CAS]
1918238-72-8 | [Synonyms]
JAK3i
JAK3i
(JAK3 inhibitor JAK3i)
7H-Pyrrolo[2,3-d]pyrimidine-5-carboxylic acid, 4-[2-fluoro-5-[(1-oxo-2-propen-1-yl)amino]phenyl]-, ethyl ester | [Molecular Formula]
C18H15FN4O3 | [MOL File]
1918238-72-8.mol | [Molecular Weight]
354.34 |
| Hazard Information | Back Directory | [Description]
JAK3i is a selective covalent inhibitor of JAK3 kinase activity. It reveals two distinct temporal waves of STAT5 phosphorylation and more potently targets the second wave, which is required for cell cycle progression and T cell proliferation. |
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