| Identification | Back Directory | [Name]
BT11 | [CAS]
1912399-75-7 | [Synonyms]
BT11
BT11;BT 11
BT-11, >98%
Methanone, 1,1'-(1,4-piperazinediyl)bis[1-[6-(1H-benzimidazol-2-yl)-2-pyridinyl]-
[4-[6-(1~{H}-benzimidazol-2-yl)pyridine-2-carbonyl]piperazin-1-yl]-[6-(1~{H}-benzimidazol-2-yl)pyridin-2-yl]methanone | [Molecular Formula]
C30H24N8O2 | [MOL File]
1912399-75-7.mol | [Molecular Weight]
528.56 |
| Hazard Information | Back Directory | [Biological Activity]
BT11 is an orally active compound that binds to lanthionine synthetase C-like 2 (LANCL2) with a Kd value of 7.7 μM and can be used for the treatment of inflammatory bowel disease. | [in vivo]
Oral administration of 8 mg/kg/day BT-11 to mice attenuates colitis. In the drug safety testing experiment in rats, oral high concentrations of BT-11 have good safety (detection concentration up to 1000 mg/kg/day). | [target]
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Tags:1912399-75-7
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