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IdentificationBack Directory
[Name]

Carbidopa 4'-Phosphate
[MDL Number]

MFCD32067873
Chemical PropertiesBack Directory
[Boiling point ]

646.1±65.0 °C(Predicted)
[density ]

1.632±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
[form ]

Solid
[pka]

1.20±0.50(Predicted)
[color ]

White to off-white
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H335-H302-H319
[Precautionary statements ]

P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P-P264-P270-P301+P312-P330-P501
Hazard InformationBack Directory
[Uses]

Foscarbidopa (ABBV-951; Carbidopa 4′-monophosphate) is a proagent of Carbidopa, acts as a dopamine receptor agonist[1][2].
[Definition]

ChEBI: Foscarbidopa is an L-tyrosine derivative that is carbidopa in which the hydroxy group at position 4' is replaced by a phosphonooxy group. It is a water-soluble prodrug of carbidopa which is used for the treatment of Parkinson's disease. It has a role as a prodrug and an antiparkinson drug. It is an O-phosphoamino acid, a L-tyrosine derivative and a non-proteinogenic L-alpha-amino acid. It is functionally related to a carbidopa (anhydrous).
[storage]

Store at -20°C
[References]

[1] Benoit CARDINAL-DAVID, et al. Carbidopa and L-Dopa Prodrugs and Methods of Use. US 20160106765 A1.
[2] International Nonproprietary Names for Pharmaceutical Substances (INN). WHO Drug Information, Vol. 32, No. 4, 2018.
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