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ChemicalBook--->CAS DataBase List--->190728-24-6

190728-24-6

190728-24-6 Structure

190728-24-6 Structure
IdentificationBack Directory
[Name]

Quinoline, 6,7-dimethoxy-4-(4-nitrophenoxy)-
[CAS]

190728-24-6
[Synonyms]

Cabozantinib Nitro Analog
Cabozantinib Genotoxic Impurity II
6,7-dimethoxy-4-(4-nitrophenoxy)-Quinoline
Quinoline, 6,7-dimethoxy-4-(4-nitrophenoxy)-
6,7-dimethoxy-4-(4-nitrophenoxy)quinolineQ: What is 6,7-dimethoxy-4-(4-nitrophenoxy)quinoline Q: What is the CAS Number of 6,7-dimethoxy-4-(4-nitrophenoxy)quinoline
[Molecular Formula]

C17H14N2O5
[MDL Number]

MFCD22581649
[MOL File]

190728-24-6.mol
[Molecular Weight]

326.3
Chemical PropertiesBack Directory
[Boiling point ]

480.9±40.0 °C(Predicted)
[density ]

1.319±0.06 g/cm3(Predicted)
[pka]

4.33±0.30(Predicted)
Hazard InformationBack Directory
[Uses]

6,7-Dimethoxy-4-(4-nitrophenoxy)quinoline is a related compound of cabozantinib (CAS# 849217-68-1) with potential anticancer activity. It can be used in the preparation of nicotinamide derivatives as Aurora kinase inhibitors, nquinolinyloxyphenylbenzenesulfonamides as AXL kinase inhibitors, N-phenyl-N'-{4-(4-quinolyloxy)phenyl}ureas as vascular endothelial growth factor receptor 2 (VEGFR-2) tyrosine kinase inhibitors, and phenoxyquinolines as specific inhibitors of platelet-derived growth factor receptor tyrosine kinase.
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