| Identification | Back Directory | [Name]
CHZ868 | [CAS]
1895895-38-1 | [Synonyms]
CHZ868
CHZ 868; CHZ-868
Acetamide, N-[4-[[2-[(2,4-difluorophenyl)amino]-1,4-dimethyl-1H-benzimidazol-5-yl]oxy]-2-pyridinyl]- | [Molecular Formula]
C22H19F2N5O2 | [MDL Number]
MFCD30533612 | [MOL File]
1895895-38-1.mol | [Molecular Weight]
423.42 |
| Chemical Properties | Back Directory | [density ]
1.37±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO:100.0(Max Conc. mg/mL);236.17(Max Conc. mM) | [form ]
Solid | [pka]
13.27±0.70(Predicted) | [color ]
White to gray |
| Hazard Information | Back Directory | [Definition]
ChEBI: CHZ868 is a memger of the class of benzimidazoles that is benzimidazole that is substituted by methyl groups at positions 1 and 4, by a 2,4-difluoroanilino group at position 2, and by a (2-acetamidopyridin-4-yl)oxy group at position 5. It is a type II JAK2 inhibitor with antineoplastic activity. It has a role as an EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor and an antineoplastic agent. It is a member of benzimidazoles, a member of acetamides, a member of pyridines, a difluorobenzene, an aromatic ether, a secondary amino compound and an aromatic amine. | [storage]
Store at -20°C |
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