Identification | Back Directory | [Name]
fenetylline hydrochloride | [CAS]
1892-80-4 | [Synonyms]
Biocapton NSC 169872 Fenetylline Fenethylline Captagon hydrochloride Amfetyline hydrochloride fenetylline hydrochloride Fenethylline hydrochloride MVXGSLGVWBVZCA-UHFFFAOYSA-N fenetylline hydrochloride USP/EP/BP 7-(Phenyl-isopropyl-amino-aethyl)-theophyllin-hydrochlorid 7-[2-[(α-Methylphenethyl)aMino]ethyl]theophylline Hydrochloride 7-[2-(1-Methyl-2-phenylethylamino)ethyl]theophylline hydrochloride 7-[2-[(.alpha.-Methylphenethyl)amino]ethyl]theophylline hydrochloride 7-[2-[(.alpha.-Methylphenethyl)amino]ethyl]theophylline monohydrochloride 3,7-Dihydro-1,3-diMethyl-7-[2-[(1-Methyl-2-phenylethyl)aMino]ethyl]-1H-purine-2,6-dione Hydrochloride 1H-Purine-2,6-dione, 3,7-dihydro-1,3-dimethyl-7-[2-[(1-methyl-2-phenylethyl)amino]ethyl]-, monohydrochloride | [EINECS(EC#)]
217-580-8 | [Molecular Formula]
C18H24ClN5O2 | [MOL File]
1892-80-4.mol | [Molecular Weight]
377.868 |
Hazard Information | Back Directory | [Originator]
Captagon,Homburg,W. Germany,1961 | [Uses]
CNS stimulant.
Controlled substance. | [Manufacturing Process]
1 mol of 7-(β-chloroethyl)-theophylline and 2? mols of α-methyl-β-phenyl
ethylamine are heated for 6 hours in an oil bath, if necessary with addition of
alcohol or toluene. The reaction mixture is diluted with alcohol and acidified
with alcoholic hydrochloric acid. The crystalline mass formed is filtered with
suction and extracted by boiling with alcohol. A product having a melting point
of 237°C to 239°C is formed. With prolonged extraction by boiling with
alcohol, the melting point of the mass falls, preferably due to a change in
modification, to 227°C to 229°C. However, analysis shows that both products
are the pure condensation product. Instead of the chloroethyl theophylline, it is also possible to use the
corresponding bromine derivative. It was found that in this way the process is
facilitated and the yield is improved | [Therapeutic Function]
Central stimulant |
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