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ChemicalBook--->CAS DataBase List--->187888-13-7

187888-13-7

187888-13-7 Structure

187888-13-7 Structure
IdentificationBack Directory
[Name]

A 40926 coMplex
[CAS]

187888-13-7
[Synonyms]

A 40926 coMplex
Parvodicin coMplex
[Molecular Formula]

C83H88Cl2N8O29
[MOL File]

187888-13-7.mol
[Molecular Weight]

1732.53
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
[form ]

A solid
Hazard InformationBack Directory
[Description]

Parvodicin complex is a mixture of closely related lipophilic glycopeptides originally isolated from A. parvosata. The parvodicin complex has activity against Gram-positive bacteria (MICs = 0.8-12.5 μg/ml) including methicillin-resistant strains of S. aureus (MRSA), S. hemolyticus, and E. faecalis (MICs = 0.1-25 μg/ml). Glycopeptide antibiotics act by preventing cell wall synthesis by binding and sequestering a cell wall precursor with a D-alanine-containing peptide.
[Uses]

Parvodicin complex is a family of glycopeptides with potent antibiotic activity, isolated from Actinomadura parvosata. Structurally the parvodicins share a common cyclic peptide core with ristocetin. The analogues within the complex vary in the fatty acid substitution on the aminosugar. Like other glycopeptides in this class, parvodicin complex inhibits cell wall formation by binding to D-alanine-D-alanine residues. Parvodicin complex is a precursor to the synthetic glycopepide, dalbavancin.
[Uses]

Parvodicin complex is an antibiotic isolation from Actinomadura parvosata.
[storage]

Store at -20°C
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