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IdentificationBack Directory
[CAS]

187888-07-9
[MDL Number]

MFCD07772395
Chemical PropertiesBack Directory
[storage temp. ]

-20°C
[form ]

buffered aqueous solution
[biological source]

rabbit
Safety DataBack Directory
[HS Code ]

3504009000
Hazard InformationBack Directory
[Biological Activity]

Endostatin inhibits the proliferation and migration of endothelial cells. It blocks apoptosis of cells and G1 to S phase transition in the cell cycle. It inhibits angiogenesis by blocking the pro-angiogenic activities of VEGF and FGF-basic. Mutations in this gene lead to Knobloch Syndrome (KS)a rare autosomal recessive disorder.
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