| Identification | Back Directory | [Name]
(1S)-1-[2-[4-[4-(AMINOCARBONYL)PHENYL]-1-PIPERAZINYL]ETHYL]-3,4-DIHYDRO-N-METHYL-1H-2-BENZOPYRAN-6-CARBOXAMIDE | [CAS]
187665-65-2 | [Synonyms]
PNU 142633
(1S)-1-[2-[4-[4-(AMINOCARBONYL)PHENYL]-1-PIPERAZINYL]ETHYL]-3,4-DIHYDRO-N-METHYL-1H-2-BENZOPYRAN-6-CARBOXAMIDE | [Molecular Formula]
C24H30N4O3 | [MDL Number]
MFCD10687093 | [MOL File]
187665-65-2.mol | [Molecular Weight]
422.52 |
| Chemical Properties | Back Directory | [Boiling point ]
652.5±55.0 °C(Predicted) | [density ]
1?+-.0.06 g/cm3(Predicted) | [storage temp. ]
Store at +4°C | [solubility ]
Soluble to 100 mM in DMSO | [form ]
Powder | [pka]
15.27±0.40(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
PNU 142633 is a high affinity SR-1D agonist. | [Biological Activity]
Very selective, high affinity 5-HT 1D receptor agonist (K i values are 6 and > 18000 nM at human 5-HT 1D and 5-HT 1B receptors respectively). Inhibits sympathetically-induced tachycardic responses and blocks neurogenic plasma protein extravasation in vivo . | [storage]
Store at +4°C |
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