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ChemicalBook--->CAS DataBase List--->186097-54-1

186097-54-1

186097-54-1 Structure

186097-54-1 Structure
IdentificationBack Directory
[Name]

DK-AH 269
[CAS]

186097-54-1
[Synonyms]

DK-AH 269;DKAH-269
Cilobradine DK-AH
Cilobradine (DK-AH 269
Cilobradine (hydrochloride)
DK-AH 269 >=98% (HPLC), solid
(S)-(+)-7,8-Dimethoxy-3-[[1-(2-(3,4-dimethoxyphenyl)ethyl)-3-piperidinyl]methyl]-1,3,4,5-tetrahydro-2H-3-benzazepin-2-one hydrochloride
Cilobradine hydrochloride, (S)-(+)-7,8-Dimethoxy-3-[[1-(2-(3,4-dimethoxyphenyl)ethyl)-3-piperidinyl]methyl]-1,3,4,5-tetrahydro-2H-3-benzazepin-2-one hydrochloride
[Molecular Formula]

C28H38N2O5.ClH
[MDL Number]

MFCD07776908
[MOL File]

186097-54-1.mol
[Molecular Weight]

519.078
Chemical PropertiesBack Directory
[storage temp. ]

2-8°C
[solubility ]

H2O: ~20 mg/mL
[form ]

solid
[color ]

white
Safety DataBack Directory
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

DK-AH 269 has been used as a hyperpolarization-activated and cyclic nucleotide-gated channel (HCN) antagonist to study its effects on the inhibition of Ih?in?HCN-deficient hair cells of mice. It has also been used as an HCN blocker to study its effects on action potential firing in the suprachiasmatic nucleus (SCN) neurons.
[Biochem/physiol Actions]

DK-AH 269 is a bradycardiac agent.
[storage]

Store at -20°C
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