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ChemicalBook--->CAS DataBase List--->185259-85-2

185259-85-2

185259-85-2 Structure

185259-85-2 Structure
IdentificationBack Directory
[Name]

3-[3-(2-DIMETHYLAMINOETHYL)-1H-INDOL-5-YL]-N-(4-METHOXYBENZYL)ACRYLAMIDE
[CAS]

185259-85-2
[Synonyms]

GR 46611
3-[3-(2-DIMETHYLAMINOETHYL)-1H-INDOL-5-YL]-N-(4-METHOXYBENZYL)ACRYLAMIDE
3-[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl]-N-[(4-methoxyphenyl)methyl]prop-2-enamide
2-Propenamide, 3-[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl]-N-[(4-methoxyphenyl)methyl]-
[Molecular Formula]

C23H27N3O2
[MDL Number]

MFCD00953517
[MOL File]

185259-85-2.mol
[Molecular Weight]

377.48
Chemical PropertiesBack Directory
[density ]

1.168
[storage temp. ]

2-8°C
[solubility ]

DMSO: 28 mg/mL, soluble
[form ]

solid
[color ]

white
Safety DataBack Directory
[Hazard Codes ]

Xi
[Risk Statements ]

36/37/38
[Safety Statements ]

26-36
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

GR 46611is a 5-HT1D agonist.
[Definition]

ChEBI: 3-[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl]-N-[(4-methoxyphenyl)methyl]-2-propenamide is a member of tryptamines.
[Biological Activity]

5-HT 1D receptor agonist. Blockade of GR 46611-induced hypothermia in the guinea pig provides a useful model with which to study the potency and duration of action of centrally acting 5-HT 1D receptor ligands.
Spectrum DetailBack Directory
[Spectrum Detail]

3-[3-(2-DIMETHYLAMINOETHYL)-1H-INDOL-5-YL]-N-(4-METHOXYBENZYL)ACRYLAMIDE(185259-85-2)1HNMR
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