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ChemicalBook--->CAS DataBase List--->1849616-42-7

1849616-42-7

1849616-42-7 Structure

1849616-42-7 Structure
IdentificationBack Directory
[Name]

/
[CAS]

1849616-42-7
[Synonyms]

Methoxypoly(ethylene glycol) ditetradecylacetamide
[Molecular Formula]

(C2H4O)nC31H63NO2
[MOL File]

1849616-42-7.mol
Questions And AnswerBack Directory
[Physical Form]

White to Yellow Solid
[Uses]

Methoxypoly(ethylene glycol) ditetradecylacetamide can be used in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.
Chemical PropertiesBack Directory
[solubility ]

DMF: 10 mg/ml; DMF:PBS (pH 7.2) (1:2): 0.3 mg/ml; DMSO: Slightly Soluble; Ethanol: 1 mg/ml
[form ]

A solid
[color ]

White to off-white
Hazard InformationBack Directory
[Description]

ALC-0159 is a PEG/lipid conjugate (i.e. PEGylated lipid), specifically, it is the N,N-dimyristylamide of 2-hydroxyacetic acid, O-pegylated to a PEG chain mass of about 2 kilodaltons (corresponding to about 45-46 ethylene oxide units per molecule of N,N-dimyristyl hydroxyacetamide). It is a non-ionic surfactant by its nature. It has been deployed in the Pfizer-BioNTech SARS-CoV-2 mRNA vaccine that contains the active ingredient tozinameran.
[Application]

ALC-0159 is a PEG/lipid conjugate (i.e. PEGylated lipid), specifically, it is the N,N-dimyristylamide of 2-hydroxyacetic acid, O-pegylated to a PEG chain mass of about 2 kilodaltons (corresponding to about 45-46 ethylene oxide units per molecule of N,N-dimyristyl hydroxyacetamide). It is a non-ionic surfactant by its nature.
[References]

[1] S Moein Moghimi, et al. Allergic Reactions and Anaphylaxis to LNP-Based COVID-19 Vaccines. Mol Ther. 2021 Mar 3;29(3):898-900. DOI:10.1016/j.ymthe.2021.01.030
Spectrum DetailBack Directory
[Spectrum Detail]

Methoxypoly(ethylene glycol) ditetradecylacetamide(1849616-42-7)1HNMR
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