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ChemicalBook--->CAS DataBase List--->1846606-32-3

1846606-32-3

1846606-32-3 Structure

1846606-32-3 Structure
IdentificationBack Directory
[Name]

Vildagliptin iMpurity A-F
[CAS]

1846606-32-3
[Synonyms]

ZA(R)-Isomer
Vildagliptin IMP
Valdagliptin impurity
Vildagliptin Impurity 29
Vildagliptin Impurity 73
Vildagliptin iMpurity A-F
(2S)-1-(aminoacetyl)pyrrolidine-2-carbonitrile
(8aS)-3-hydroxyhexahydropyrrolo[1,2-a]pyrazine-1,4-dione
Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-3-hydroxy-, (8aS)-
[Molecular Formula]

C7H10N2O3
[MDL Number]

MFCD34179904
[MOL File]

1846606-32-3.mol
[Molecular Weight]

170.17
Chemical PropertiesBack Directory
[Boiling point ]

535.5±50.0 °C(Predicted)
[density ]

1.48±0.1 g/cm3(Predicted)
[pka]

11.63±0.20(Predicted)
Hazard InformationBack Directory
[Uses]

3-Hydroxyhexahydropyrrolo[1,2-a]pyrazine-1,4-dione is an impurity of Vildagliptin (V305000), part of a class of oral anti-hyperglycemic agents that inhibit dipeptidyl peptidase 4 (DPP-4), which can act as a serine exopeptidase. Aside from their use in type 2 diabetes, gliptins have positive cardiovascular and anti-inflammtatory effects. Antidiabetic.
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