| Identification | Back Directory | [Name]
Acid-PEG3-NHS ester | [CAS]
1835759-79-9 | [Synonyms]
COOH-PEG3-NHS
COOH-PEG3-SPA
Acid-PEG3-NHS ester
Acid-C2-PEG3-NHS ester
Propanoic acid, 3-[2-[2-(2-carboxyethoxy)ethoxy]ethoxy]-, 1-(2,5-dioxo-1-pyrrolidinyl) ester | [Molecular Formula]
C14H21NO9 | [MDL Number]
MFCD29052171 | [MOL File]
1835759-79-9.mol | [Molecular Weight]
347.32 |
| Chemical Properties | Back Directory | [Boiling point ]
516.1±60.0 °C(Predicted) | [density ]
1.34±0.1 g/cm3(Predicted) | [solubility ]
Soluble in DMSO, DCM, DMF | [pka]
4.28±0.10(Predicted) |
| Hazard Information | Back Directory | [Description]
Acid-PEG3-NHS ester is a PEG linker containing a carboxylic acid and an NHS ester. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. |
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