| Identification | Back Directory | [Name]
YM-53601 | [CAS]
182959-33-7 | [Synonyms]
YM-53601 Exclusive
2-[(2E)-2-(1-azabicyclo[2.2.2]octan-3-ylidene)-2-fluoroethoxy]-9H-carbazole:hydrochloride
2-[(2E)-2-(1-azabicyclo[2.2.2]oct-3-ylidene)-2-fluoroethoxy]-9H-carbazole, monohydrochloride | [Molecular Formula]
C21H21FN2O.ClH | [MDL Number]
MFCD06411577 | [MOL File]
182959-33-7.mol | [Molecular Weight]
372.869 |
| Chemical Properties | Back Directory | [Melting point ]
236.5-237.2 °C | [storage temp. ]
Store at -20°C | [solubility ]
DMF: 20 mg/ml; DMSO: 20 mg/ml; DMSO:PBS(pH 7.2) (1:3): 0.25 mg/ml; Ethanol: 2 mg/ml | [form ]
A crystalline solid | [color ]
Off-white to light brown |
| Hazard Information | Back Directory | [Uses]
YM-53601 is a squalene synthetase inhibitor. | [Definition]
ChEBI: YM-53601 is a member of carbazoles. | [Biological Activity]
Squalene synthase inhibitor.
YM-53601 is a cell penetrant and potent squalene synthase inhibitor inhibits cholesterol biosynthesis in rodents. YM-53601 lowers cholesterol levels and triglyceride levels better than HMG-CoA reductase inhibitor (prevastatin) and fibrate (fenofibrate.). | [storage]
Store at -20°C |
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BOC Sciences
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DC Chemicals
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